This course in enzyme (also known as bio-catalysts) an protein engineering aims to familiarize participants with the integrated, interdisciplinary approach required to utilize the catalytic potential of enzymes and whole cells for the production of useful compounds. Organic chemists, enzymologists, microbiologists and (bio)chemical engineers will offer a selection of theory and practice in the application of the study. In this way, the course will provide an intensive and in-depth treatment of the state of the art and the necessary link between fundamental knowledge and practical applications in industrial scale processes. Students should be able to understand and explain differences between rational design and directed evolution, and have a general knowledge about miscellaneous topics such as searches in bioinformatics databases, isolation, expression or purification of novel proteins